News and Updates for Healthcare Professionals

A cross-sectional study analyzed the changing use of medications and dietary supplements in the U.S. between 2015-2016 and 2021-2023. Polypharmacy involving prescription medications and dietary supplements rose between these periods. The proportion of people with potentially major interacting drug regimens or drug-drug interactions fell, but still stood at more than…

An exclusive collection of 12 clinical guideline summaries that will directly impact how you practice medicine. Inside this new NEJM Clinician content collection, discover 12 new and updated guideline summaries to help you stay informed and confident in your practice.

Summaries and highlights of the most important new clinical guidelines to inform your practice

The “2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome” retires, replaces, and expands upon the “2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults.” The primary intended audience for this guideline is clinicians who care for patients across the spectrum of cardiovascular-kidney-metabolic…

This collection provides an abridged version of the American Diabetes Association’s (ADA’s) Standards of Care in Diabetes—2026 designed especially for primary care professionals. Developed by the ADA’s Primary Care Advisory Group*, this new resource contains the evidence-based clinical practice recommendations most pertinent to primary care—all presented in a user-friendly format.…

This guideline establishes clinical practice recommendations for combination treatment of chronic insomnia disorder in adults, defined here as treatment with cognitive-behavioral therapy for insomnia (CBT-I) started concurrently with pharmacotherapy.

Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos. The objective of this guideline from a Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) panel is to expand on current cardiovascular guidelines to include evidence from…

Since 1940, the American Diabetes Association® has been a trusted source for cutting-edge diabetes care education solutions. Our Institute of Learning offers 70+ free continuing education courses, webinars, and more to help you stay ahead of the curve.

The “2026 Guideline for the Early Management of Patients With AIS” replaces the “2018 Guidelines for the Early Management of Patients With AIS” and the 2019 update to reflect recent advances in evidence. This updated guideline is intended to provide a comprehensive, up-to-date, evidence-based set of recommendations, advising management from…

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released the 2026 updated version of its Global Strategy for Prevention, Diagnosis and Management of Chronic Obstructive Pulmonary Disease.